Searchable abstracts of presentations at key conferences in endocrinology

ea0042p15 | (1) | Androgens2016

Altered steroid profiles in prostate cancer xenograft model with low ADRB2 levels

Ramberg Hakon , Kellman Ralf , Braadland Peder Rustoen , Staerli Elin , Waagene Stein , Mellgren Gunnar , Maelandsmo Gunhild Mari , Tasken Kristin Austlid

It has been established in recent years that androgens are involved in the progression of castration resistant prostate cancer (CRPC). Although androgen deprivation therapy reduces the level of androgens and inhibits the androgen receptor, there are studies reporting that the androgen signaling axis is still involved in the development of CRPC. We have in a previous study shown that low level of β2-adrenergic receptor (ADRB2) is associated with shorter time to ...